People

Steering Members

 

Andrey Abramov

Pathophysiological mechanisms of mitochondrial mutations associated with Parkinson’s Disease

Institute of Neurology
Michelangelo Campanella

Roles of the mitochondrial proteins IF1 and the mitochondrial benzodiazepine receptor in the regulation of cell fate and disease

Department of Comparative Biomedical Sciences, Royal Veterinary School
Michael Duchen

Neurodegenerative diseases; mitochondrial genetic disease; comparative mitochondrial cell biology; fluorescence imaging of mitochondrial function; cell death pathways

Department of Cell and Developmental Biology
Josef Kittler

Cell biological mechanisms underlying neuronal excitability and synaptic plasticity. Mitochondrial trafficking in neurons.

Department of Neuroscience, Physiology and Pharmacology
Nick Lane

Mitochondrial genetics and evolution

Department of Genetics, Evolution and Environment
Amandine Marechal

Structural & Molecular Biology

Faculty of Life Sciences, Division of Biosciences
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Shamima Rahman

Mitochondrial DNA replication and mutations.

Institute of Child Health
Peter R. Rich

Biological electron transfer. Infrared spectroscopy.

The Glynn Laboratory of Bioenergetics at UCL
Department of Structural and Molecular Biology
Gyorgy Szabadkai

Mitochondrial biogenesis and cancer; mitochondria and calcium signalling; mitochondria and cell death

Department of Cell and Developmental Biology, UCL
Department of Biomedical Sciences, University of Padua
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UCL Associates

 

Neil Bradman

Use of genetic variation in the study of demographic history, pharmacogenetics

The Centre for Genetic Anthropology
Mike Cheetham

Neurodegeneration

Department: UCL Institute of Ophtalmology
Mike_Cheetham
Shamshad Cockcroft

Basic Life Sciences, Cancer, Infection & Immunology and Inflammation, Neuroscience, Personalised Medicine

Department: Division of Biosciences, Faculty of Life Sciences
J. Mark Cooper

Neurodegenerative diseases, in particular the investigation of the molecular mechanisms of Parkinson's disease

Department: Clinical Neurocience, UCL Institute of Neurology

Martin Crompton

Mitochondria; Permeability transition; Calcium; Oxidative stress, Cyclophilins; Cell death
Clare Elwell

Development of novel optical systems for monitoring the healthy and injured brain 

Department: Medical Physics and Bioengineering
Elizabeth Fisher

The neurogenetics of neurodegenerative disease

Department: Neurodegenerative Diseases, UCL Institute of Neurology
Lazaros Foukas

Mammalian PI 3-kinase signalling and ageing

Department: Institute of Healthy Ageing, UCL Genetics, Evolution and Environment
Jonathan Gale

Repair and regeneration of hair epithelia; mitochondrial dysfunction in deafness

Department: Ear Institute
Alex Gourine

Autonomic neuroscience

Department: Neuroscience, Physiology & Pharmacology
Ivan Gout

Regulation of growth and energy metabolism via the mTOR/S6K pathway in normal and cancer cells

Department: Structural and Molecular Biology
Linda Greensmith

Development and Neurodegeneration of Motor Neurons; Motor Neuron Diseases; Neuromuscular Diseases 

Department: Sobell Research Department of Motor Neuroscience & Movement Disorders
Michael Hanna

Human neuromuscular diseases and diseases related to mtDNA mutations

Department: Institute of Neurology
John Hardy

Neurological disease. Genetic studies of neurological disease, population genetics

Department: Molecular Neuroscience, UCL Institute of Neurology
Simon Heales

Mitochondrial dysfunction and oxidative stress in neurodegenerative disease

Department: Institute of Neurology
Chris Kay

EPR Spectroscopy

Department: Structural & Molecular Biology
London Centre for Nanotechnology
Mark Lythgoe

Biomedical Imaging

Department: Centre for Advanced Biomedical Imaging
Vidya Mohamed-Ali

Biology of adipocytes and the role of adipose tissue as an endocrine organ. Regulation of metabolism and obesity 

Department: Metabolism and Experimental Therapeutics
Hugh Montgomery

Critical care medicine; hypoxic adaptation; human performance; renin-angiotensin systems

Department: Division of Medicine
Steve Moss
 
Department: Institute of Ophthalmology
Francesco Muntoni

Paediatric neurology, neuromuscular disease

Department: Neurosciences & Mental Health, UCL Institute of Child Health
Richard Orrell

Clinical Neurosciences and Consultant Neurologist

Department: Clinical Neurosciences, Institute of Neurology
Helene Plun-Favreau

Parkinson's Disease

Department: Institute of Neurology, Faculty of Brain Sciences
Linda Partridge

Biology of Ageing 

Department: Genetics, Evolution & Environment
Andrew Pomiankowski

evolution and consequences of sexual reproduction, from early forms of living systems to complex eukaryotic life

Department: Genetics, Evolution and Environment
Saul Purton

The biology and biotechnology of algae

Department: Structural & Molecular Biology
Bill Richardson

Properties and functions of neural stem cells and their progeny in the embryonic and postnatal CNS

Department: Wolfson Institute of Biomedical Research
Anthony Schapira

Neurodegenerative diseases, particularly Parkinson's disease, Huntington's disease and Friedreich's Ataxia. Interest is mainly focused on the molecular mechanisms involved in pathogenesis. Additional research: mitochondrial dysfunction

Department: Clinical Neurocience, UCL Institute of Neurology
David Selwood

Chemistry of Mitochondria targeted Therapeutic Tools

Department: Chemistry
Kenneth Smith

Pathophysiology of inflammatory demyelinating disease; Electrophysiology; Imaging; Nitric oxide

Department: Neuroinflammation, UCL Institute of Neurology
Paul Simons

Neural development; Ageing; Neurodegeneration; Myloidosis

Department: Inflammation, UCL Division of Medicine
Mervyn Singer

Sepsis; Multiple organ failure; Infection; Haemodynamics; Haemodynamic monitoring

Department: Clinical Physiology, UCL Division of Medicine
Antonella Spinazzola

Mitochondrial biogenesis and disease

Department: Clinical Neurocience, UCL Institute of Neurology
Jan-Willem Taanman

Experimental cell culture models of neurodegenerative disease, including Parkinson's disease and mitochondrial encephalomyopathies

Department: Clinical Neurocience, UCL Institute of Neurology
Robert Unwin

Renal tubular physiology and the regulation of ion transport

Department: Internal Medicine, UCL Division of Medicine
Jonathan Wilden

Department: Chemistry
Nicholas Wood

Genetic basis of neurodegenerative disease

Department: Wolfson Institute of Biomedical Research
Derek Yellon

The pathophysiology of ischaemia-reperfusion injury in the basic and clinical arena

Department: Cardiovascular Medicine, UCL Division of Medicine

External & Former Associates

 

Chris Cooper
University of Essex School of Biological Sciences
Non-invasive cytochrome oxidase measurements and mitochondrial kinetic modelling
Honorary Professor of UCL in the Department of Medical Physics and Bioengineering
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Ian Holt

Mitochondrial DNA replication and mitochondrial disease
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Nick Jones

Imperial College London, Department of Mathematics

Mitochondrial variability and bioenergetics
Patrick Maxwell

University of Cambridge, Cambridge Institute for Medical Research

Oxygen sensing; von Hippel Lindau disease;  Renal cancer; Genetics of renal disease
maxwell
Karl Morten

University of Oxford, Nuffield Department of Obstetrics and Gynecology

Energy Metabolism & Cancer, Mitochondrial Toxicity
Joanna Poulton

University of Oxford, Nuffield Department of Obstetrics and Gynecology

Mitophagy and Mitochondrial DNA Maintenance
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Dominic Withers

Imperial College London, Institute of Clinical Sciences

The central nervous system regulation of energy homeostasis
withers
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